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. Author manuscript; available in PMC: 2018 Dec 12.
Published in final edited form as: ACS Biomater Sci Eng. 2018 Feb 3;4(3):900–918. doi: 10.1021/acsbiomaterials.7b00831

Figure 4.

Figure 4

Secretion of IL-12 is stymied when DCs are cocultured with low molecular weight PLGA/PLA MPs, particularly after LPS stimulation. (A) Supernatants were collected from DCs cocultured with PLGA or PLA, and IL-12 was quantified using an absorbance-based sandwich ELISA. The * symbol represents a pairwise comparison to the immature DC population (p ≤ 0.05). (B) Supernatants were collected from DCs cocultured with PLGA or PLA and then challenged with 1.5 μg/mL LPS. IL-12 was quantified using a sandwich ELISA. The * symbol represents a pairwise comparison to the immature DC population (p ≤ 0.05). Data shown represent mean cytokine concentration ± standard error (n ≥ 3 biological replicates).