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. Author manuscript; available in PMC: 2019 Aug 3.
Published in final edited form as: Expert Opin Drug Metab Toxicol. 2018 Aug 3;14(8):817–829. doi: 10.1080/17425255.2018.1499726

Figure 1: Schematic illustration of human placenta with cross-section through a chorionic villus.

Figure 1:

P-gp and BCRP are localized on the microvillous membrane (apical membrane) of the syncytiotrophoblasts. BCRP is also expressed in fetal capillary endothelium. First trimester immunostaining also revealed BCRP and P-gp expression in the cytotrophoblasts. Arrows indicate the direction of transport. [29–32, 44, 62–67]