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. Author manuscript; available in PMC: 2019 Aug 3.
Published in final edited form as: Expert Opin Drug Metab Toxicol. 2018 Aug 3;14(8):817–829. doi: 10.1080/17425255.2018.1499726

Figure 2: Schematic illustration of rodent placenta (mouse and rat) from the fetal to maternal interface.

Figure 2:

P-gp and Bcrp are mainly expressed on the apical membrane of the syncytiotrophoblast layer II. Arrows indicate the direction of transport. Bcrp is also expressed in the fetal capillary endothelium; however, at present, no information is available about cellular localization and function of Bcrp in fetal capillary endothelium. Therefore, the direction of transport of Bcrp in fetal capillary endothelium is unknown. [32–37, 68–70]