. Author manuscript; available in PMC: 2018 Dec 12.

Published in final edited form as: J Ment Health Clin Psychol. 2018 Apr 16;2(2):17–24.

Table 2.

Cytochrome P450 CYP1A2 Enzyme Substrates, Inhibitors and Inducers.

Cytochrome P450 Gene	Drugs or Substrates	Inhibitors	Inducers
CYP1A2	Agomelatine, Amitriptyline (Elavil®), Caffeine, Clomipramine (Anafranil®), Clozapine (Clozaril®), Cyclobenzaprine (Flexeril®), Erlotinib (Tarceva®), Estradiol, Fluvoxamine (Luvox®), Imipramine (Trofranil®), Haloperidol (Haldol®), Melatonin, Mexiletine (Mexitil®), Naproxen, Olanzapine (Zyprexa®), Ondansetron (Zofran®), Propranolol, Ropivacaine, (Naropin®), Tacrine (Cognex®), Theophyline (Theolair®), Verapamil (Covera-HS®), Warfarin (Coumadin®), Zolmitriptan (Zomig®)	Amiodarone (Cordarone®), Cimetidine (Tagamet®), Ciprofloxacin (Cipro®), Cumin, Fluroquinolones, Fluvoxamine (Luvox®), Interferon, Methoxsalen (Uvadex®), Milbefradil	Beta-Naphthoflavone, Broccoli, Brussel sprouts, Cabbage Cauliflower Insulin, Methylcholanthrene, Modafinil (Provigil®), Nafcillin, Omeprazole (Prilosec®), Tobacco