Bhlhe40−/− mice have
normal numbers of mast cells and develop passive cutaneous anaphylaxis and
passive systemic anaphylaxis normally. A. Flow analysis of
peritoneal cavity mast cells and total number of peritoneal cavity mast
cells (mean ± SEM, n=3 mice) (left panel). Toluidine
blue staining of mast cells (281 magnification ×40; insert,
×100). Mast cells are indicated by arrows. Average number of mast
cells in ten randomly selected fields (×40) (mean ± SEM, n=3
mice) (right panels). B. PCA analysis, mean
± SEM, n=3 mice. C. PSA analysis, mean ± SEM, n=3
mice. FIG E9 related to FIG 3.