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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Dec 24;142(4):1173–1184. doi: 10.1016/j.jaci.2017.10.043

FIG E12.

FIG E12.

MITF drives the −8.8 enhancer activity. A, Luciferase reporter gene analysis of Hdc enhancer activities in CFTL-15 cells with knocked down Mitf mRNA or shRNA control (mean ± SEM, triplicates). B. Luciferase reporter gene analysis of the Hdc enhancer activities in HEK293 cells co-transfected with vector control or the MITF expression construct (mean ± SEM, triplicates). C. Luciferase reporter gene analysis of the activity of Hdc enhancers that have a mutated MITF binding site(s) (mean ± SEM, triplicates). The left and right panels (A, B, and C) or the upper and lower panel (D) each show two independent experiments. FIG E12A related to FIG 6A; FIG E12B related to FIG 6B; FIG E12C related to FIG 6C.