Transcription factors AHR, AHRR, BHLHE40, and MITF depend on GATA2 for
their expression in mast cells. A, Microarray analysis of
transcription factor expression profiles in BMMCs versus basophils.
B, qPCR analysis of mRNA expression in BMMCs versus basophils.
The numbers indicate the fold of difference in mRNA expression between basophils
and BMMCs (mean ± SEM, n=3 samples from 3 individual mice).
C, qPCR analysis of mRNA expression in
Gata2+/+ or
Gata2−/− BMMCs (mean ± SEM,
n=3 samples from 3 individual mice).