Table 2. Baseline characteristics by CAC or SIS categories.
| CAC 0 | CAC 1–99 | CAC 100–299 | CAC ≥300 | p value | SIS 0 | SIS 1 | SIS 2–3 | SIS ≥4 | p value | |
|---|---|---|---|---|---|---|---|---|---|---|
| (N = 4858) | (N = 2060) | (N = 623) | (N = 475) | (N = 4969) | (N = 1254) | (N = 1097) | (N = 696) | |||
| Age | 53.5±11.5 | 60.9±9.9 | 65.1±9.1 | 68.0±9.4 | <0.001 | 54.0±11.6 | 60.3±10.4 | 62.3±9.9 | 65.6±10.1 | <0.001 |
| Male gender | 2273 (46.8) | 1190 (57.8) | 381 (61.2) | 308 (64.8) | <0.001 | 2343 (47.2) | 698 (55.7) | 668 (60.9) | 443 (63.6) | <0.001 |
| Hypertension | 2128 (43.8) | 1136 (55.1) | 366 (58.7) | 300 (63.2) | <0.001 | 2204 (44.4) | 665 (53.0) | 611 (55.7) | 450 (64.7) | <0.001 |
| Diabetes mellitus | 423 (8.7) | 338 (16.4) | 111 (17.8) | 106 (22.3) | <0.001 | 461 (9.3) | 173 (13.8) | 198 (18.0) | 146 (21.0) | <0.001 |
| Dyslipidemia | 2561 (52.7) | 1277 (62.0) | 422 (67.7) | 284 (59.8) | <0.001 | 2620 (52.7) | 782 (62.4) | 684 (62.4) | 458 (65.8) | <0.001 |
| Family history | 1176 (24.2) | 507 (24.6) | 169 (27.1) | 130 (27.4) | 0.219 | 1195 (24.0) | 290 (23.1) | 322 (29.4) | 175 (25.1) | 0.001 |
| Current smoking | 757 (15.6) | 327 (15.9) | 103 (16.5) | 90 (18.9) | 0.279 | 777 (15.6) | 202 (16.1) | 174 (15.9) | 124 (17.8) | 0.532 |
| Body mass index | 26.4±4.8 | 26.0±4.5 | 26.2±5.0 | 26.2±4.7 | 0.012 | 26.4±4.7 | 26.2±4.9 | 26.1±4.9 | 25.9±4.6 | 0.007 |
| Renal insufficiency | 9 (0.2) | 5 (0.2) | 1 (0.2) | 1 (0.2) | 0.968 | 8 (0.2) | 3 (0.2) | 5 (0.5) | 0 | 0.201 |
| Peripheral vascular disease | 70 (1.4) | 22 (1.1) | 9 (1.4) | 11 (2.3) | 0.259 | 66 (1.3) | 22 (1.8) | 11 (1.0) | 13 (1.9) | 0.242 |
| Cerebrovascular disease | 38 (0.8) | 17 (0.8) | 8 (1.3) | 10 (2.1) | 0.187 | 33 (0.7) | 16 (1.3) | 12 (1.1) | 12 (1.7) | 0.201 |
| Total cholesterol | 194.5±45.0 | 187.7±39.8 | 183.8±37.0 | 189.6±37.1 | <0.001 | 194.2±45.1 | 187.3±42.1 | 187.3±34.5 | 187.2±36.6 | <0.001 |
| LDL cholesterol | 119.8±37.3 | 115.6±33.1 | 112.2±31.3 | 116.0±32.5 | <0.001 | 119.8±38.0 | 114.1±31.7 | 114.9±29.2 | 115.6±31.5 | <0.001 |
| HDL cholesterol | 54.4±16.6 | 52.2±15.9 | 52.9±16.4 | 52.4±13.8 | <0.001 | 54.0±16.4 | 53.6±16.9 | 53.0±15.8 | 52.2±15.1 | 0.115 |
| CAC | 0 | 29.9±27.4 | 174.9±56.3 | 748.1±671.9 | <0.001 | 9.7±123.5 | 45.4±141.8 | 121.3±239.9 | 413.8±538.8 | <0.001 |
| SIS | 0.2±0.6 | 1.4±1.4 | 3.0±2.0 | 4.5±2.5 | <0.001 | 0 | 1.0±0.0 | 2.4±0.5 | 5.4±1.7 | <0.001 |
LDL, low-density lipoprotein; HDL, high-density lipoprotein; CAC, coronary artery calcium; SIS, segment involvement score.