Table 3. Adjusted association between all-cause mortality, CAC, SIS, and baseline statin therapya.
| Overall population | Without statin therapy | With statin therapy | ||||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) |
p value | Hazard ratio (95% CI) |
p value | Hazard ratio (95% CI) |
p value | |
| CAC 0 | 1.00 | 1.00 | 1.00 | |||
| CAC 1–99 | 1.29 (0.76–2.17) |
0.346 | 1.65 (0.92–2.95) |
0.097 | 0.56 (0.17–1.91) |
0.357 |
| CAC 100–299 | 1.90 (1.00–3.61) |
0.052 | 2.19 (1.04–4.65) |
0.041 | 1.19 (0.34–4.19) |
0.789 |
| CAC ≥300 | 2.86 (1.55–5.27) |
<0.001 | 2.98 (1.44–6.16) |
0.004 | 3.05 (0.92–10.09) |
0.068 |
| SIS 0 | 1.00 | 1.00 | 1.00 | |||
| SIS 1 | 1.54 (0.85–2.78) |
0.154 | 1.62 (0.81–3.24) |
0.171 | 1.37 (0.44–4.29) |
0.586 |
| SIS 2–3 | 2.25 (1.32–3.83) |
0.003 | 2.48 (1.34–4.61) |
0.004 | 1.62 (0.56–4.71) |
0.375 |
| SIS ≥4 | 2.07 (1.13–3.77) |
0.019 | 2.95 (1.50–5.81) |
0.002 | 0.84 (0.21–3.33) |
0.800 |
CAC, coronary artery calcium; SIS, segment involvement score.
aAdjusted for age, male gender, hypertension, diabetes mellitus, dyslipidemia, family history and current smoking.