TABLE 6.
FISHER EXACT TEST FOR ASSOCIATION BETWEEN CLINICAL FEATURES AND CLASS 1B GENE EXPRESSION PROFILE AMONG 127 SUSPICIOUS CLASS 1 CHOROIDAL MELANOCYTIC TUMORS
| VARIABLE | Class 1A N (%) |
Class 1B N (%) |
P-VALUE |
|---|---|---|---|
| Tumor thickness >2.25 mm | No: 35 (27.6) Yes: 52 (41.0) |
No: 13 (10.2) Yes: 27 (21.3) |
.4 |
| Female sex | No: 39 (30.7) Yes: 48 (37.8) |
No: 19 (15.0) Yes: 21 (16.5) |
.4 |
| Absence of any chronic RPE features | No: 54 (42.5) Yes: 33 (26.0) |
No: 22 (17.3) Yes: 18 (14.2) |
.6 |
| Tumor margin <3 mm from disc | No: 41 (32.5) Yes: 45 (35.7) |
No: 22 (17.5) Yes: 18 (14.3) |
.6 |
| Visual symptoms | No: 36 (28.4) Yes: 51 (40.2) |
No: 18 (14.2) Yes: 22 (17.3) |
.7 |
| Absence of drusen | No: 69 (54.8) Yes: 18 (14.3) |
No: 30 (23.8) Yes: 9 (7.1) |
.8 |
| Absence of RPE fibrosis | No: 76 (60.3) Yes: 11 (8.7) |
No: 33 (26.2) Yes: 6 (4.8) |
.8 |
| Largest basal tumor diameter >12 mm | No: 67 (52.8) Yes: 20 (15.8) |
No: 32 (25.2) Yes: 8 (6.3) |
.8 |
| Presence of subretinal fluid | No: 22 (19.0) Yes: 57 (49.1) |
No: 9 (7.8) Yes: 28 (24.1) |
.8 |
| Age >60 years | No: 47 (37.1) Yes: 40 (31.5) |
No: 21 (16.5) Yes: 19 (15.0) |
1.0 |
| Absence of RPE atrophy | No: 67 (53.6) Yes: 18 (14.4) |
No: 31 (24.8) Yes: 9 (7.2) |
1.0 |
| Low acoustic internal reflectivity | No: 10 (19.6) Yes: 23 (45.1) |
No: 6 (11.8) Yes: 12 (23.5) |
1.0 |
| Presence of orange pigment | No: 35 (27.8) Yes: 52 (41.3) |
No: 16 (12.7) Yes: 23 (18.3) |
1.0 |
RPE, retinal pigment epithelium. Chronic RPE features include fibrosis, drusen and atrophy. Percentages may not add to 100% due to rounding.