Table 3.
Changes of single white matter pathways and correlation with course of language function.
| Patient | Number of fibers at PRE-1 | AG | % Difference between PRE-1 and POST-1 | LF | % Difference between POST-1 and PRE-2 | LF | % Difference between PRE-1 and PRE-2 | LF | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IFOF | FAT | SLF/AF | Total | IFOF | FAT | SLF/AF | Total | IFOF | FAT | SLF/AF | Total | IFOF | FAT | SLF/AF | Total | |||||
| 1 | 567 | 2890 | 3934 | 7391 | 0 | −85.9 | −83.1 | −67.5 | −75.0 | W | 1866.3 | −22.9 | −36.7 | 49.4 | U | 177.4 | −87.0 | −79.4 | −62.7 | W |
| 2 | 833 | 483 | 2982 | 4298 | 0 | −37.2 | −93.2 | −78.8 | −72.4 | W | −99.0 | 648.5 | 29.4 | −9.9 | I | −99.4 | −48.9 | −72.6 | −75.1 | U |
| 3 | 392 | 86 | 274 | 752 | 0 | −66.8 | −100 | −26.6 | −56.0 | W | 0.8 | – | 102.5 | 76.1 | I | −66.6 | −47.7 | 48.5 | −22.5 | U |
| 4 | 124 | 3 | 4223 | 4350 | 0 | −98.4 | −100 | −99.4 | −99.4 | W | 1700.0 | – | 2215.4 | 2192.9 | I | −71.0 | 33.3 | −85.7 | −85.2 | U |
| 5 | 51 | 0 | 38 | 89 | 1B | −23.5 | – | 189.5 | 82.0 | U | 1564.1 | −69.2 | −100 | 303.1 | W | 1172.5 | – | −100 | 633.7 | W |
| 6 | 2150 | 6 | 8499 | 10655 | 0 | −78.9 | −100 | −95.9 | −92.4 | U | −96.3 | – | −98.3 | −97.1 | W | −99.2 | −100 | −99.9 | −99.8 | W |
| 7 | 8747 | 1522 | 6588 | 16857 | 0 | −86.7 | −61.8 | −97.3 | −88.6 | U | −99.5 | −100 | −84.8 | −98.3 | W | −99.9 | −100 | −99.6 | −99.8 | W |
| 8 | 416 | 0 | 2231 | 2647 | 2B | −98.3 | – | −17.3 | −23.6 | U | 14471.4 | −43.9 | 49.8 | 91.8 | U | 145.2 | – | 23.8 | 46.5 | U |
| 9 | 109 | 110 | 682 | 901 | 0 | 138.5 | −100 | −76.7 | −53.5 | U | 573.1 | – | 1059.7 | 758.0 | U | 1505.5 | −99.1 | 170.4 | 299.0 | U |
| 10 | 201 | 0 | 62 | 263 | 0 | 613.4 | – | 7466.1 | 2228.9 | U | −85.5 | – | −41.0 | −43.3 | U | 3.5 | – | 4366.1 | 1220.5 | U |
The table shows the absolute number of fibers for each of the separately tracked subcortical pathways at PRE-1, the initial aphasia grading at PRE-1, and the percentage changes of nrTMS-based DTI FTs between PRE-1 and POST-1, POST-1, and PRE-2, and PRE-1, and PRE-2 as well as the changes of language function in all patients. The table also shows the correlation of the course of language function in each patient and the according difference of fibers of each single white matter pathway. Percentages highlighted in green indicate a correlation of the percentage changes of single white matter pathways and the according course of language function. Percentages highlighted in red indicate a lack correlation of the percentage changes of single white matter pathways and the according course of language function (AF, aphasia grading at PRE-1, LF, language function; W, worsened; U, unchanged; I, improved).