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Body weight, nesting, and locomotion are altered by cuprizone and partially rescued by DMS. (A) Weight changes in mice subjected to different treatments. (B) Representative images of nests built by control (a), model (b), LFS (c), and HFS (d) mice. (C) Histogram of nesting scores. (D) Total movement distance in 10 min. (E) Center zone movement distance in 10 min. Values are expressed as mean ± SEM (n = 12–15). **P < 0.01 vs. control group; #P < 0.05 vs. model group.
