Table 2.
Subjects characteristics.
aMCI (n = 16) | HC (n = 16) | p-value | |
---|---|---|---|
Age (years) | 73 ± 6.6 | 70 ± 3.9 | NS |
Education (years) | 10.25 ± 4.55 | 13 ± 4.81 | NS |
Left hippocampal volume (%) | 0.230 ± 0.039 | 0.288 ± 0.043 | <0.001 |
Right hippocampal volume (%) | 0.223 ± 0.030 | 0.285 ± 0.036 | <0.001 |
MMSE | 25.00 ± 2.62 | 28.21 ± 1.42 | 0.002 |
FCSRT immediate free recall | 15.95 ± 7.60 | 28.21 ± 1.42 | <0.001 |
FCSRT delayed free recall | 3.57 ± 3.42 | 10.47 ± 1.53 | <0.001 |
FCSRT immediate total recall | 28.93 ± 6.45 | 35.93 ± 0.25 | <0.001 |
FCSRT delayed total recall | 7.68 ± 3.32 | 12 ± 0 | <0.001 |
FCSRT index of sensitivity | 0.70 ± 0.20 | 0.99 ± 0.02 | <0.001 |
BDI | 9.6 ± 8 | 7.1 ± 4.9 | NS |
FAB | 14.35 ± 2.80 | 16.44 ± 1.19 | 0.010 |
Rey’s 15 word immediate recall | 26.27 ± 5.98 | 44.23 ± 7.76 | <0.001 |
Rey’s 15 word delayed recall | 3.56 ± 1.89 | 10.53 ± 3.21 | <0.001 |
Word fluency | 32.87 ± 11.29 | 32.71 ± 6.49 | NS |
Phrase construction | 14.56 ± 8.15 | 18.14 ± 5.67 | NS |
Raven’s 47 progressive matrices | 22.3 ± 5.65 | 28.03 ± 4.34 | 0.003 |
Immediate visual memory | 16.10 ± 3.77 | 19.87 ± 1.88 | 0.001 |
Freehand copying of drawings | 8.41 ± 1.36 | 9.98 ± 1.38 | 0.003 |
Copying drawings with landmarks | 65.57 ± 3.78 | 68.58 ± 4.58 | NS |
Demographic and clinical variables comparison in aMCI and control groups. Data are given as mean ± standard deviation (SD). NS, not significant; aMCI, amnestic Mild Cognitive Impairment group; HC, healthy controls; MMSE, Mini Mental State Examination; FCSRT, Free and Cued Selective Reminding Test; BDI, Beck Depression Inventory; FAB, Frontal Assessment Battery.