Table 1.
Relationship between lncRNA ANRIL expression and their clinicopathologic parameters in 49 of HNSCC patients
| Clinicopathologic parameters | Number of cases | Median expression of lncRNA ANRIL | |
|---|---|---|---|
|
| |||
| Mean ± s.d. | P-value | ||
| Gender | |||
| Male | 28 | 1.6992±0.3211 | 0.7 |
| Female | 21 | 1.4165±0.3091 | |
| Ages, years | |||
| ≤ 59 | 24 | 1.6667±0.3402 | 0.336 |
| > 59 | 25 | 1.4753±0.2951 | |
| T stage, TNM | |||
| T1+T2 | 37 | 1.3665±0.2247 | 0.005 |
| T3+T4 | 12 | 1.7262±0.4983 | |
| Clinical stage | |||
| I-II | 18 | 1.2038±0.2692 | 0.058 |
| III-IV | 31 | 1.7124±0.3181 | |
| Lymph node metastasis | |||
| Absent | 26 | 1.1078±0.2173 | 0.001 |
| Present | 23 | 1.6925±0.3529 | |
| Alcohol drinking | |||
| Absent | 27 | 1.4706±0.2830 | 0.427 |
| Present | 22 | 1.7131±0.3652 | |
| Smoking | |||
| Absent | 30 | 1.6199±0.2958 | 0.335 |
| Present | 19 | 1.4911±0.3421 | |
| Location | |||
| Lips | 12 | 1.8201±0.5256 | |
| Cheek | 5 | 1.0918±0.4883 | 0.304 |
| Buccal mucosa | 13 | 1.2690±0.3520 | |
| Tongue | 19 | 1.6466±0.3778 | |
Abbreviations: HNSCC, head and neck squamous cell carcinoma; TNM, tumor node metastasis. P-value represents the probability from a Student’s t-test for lncRNA ANRIL expression between variable subgroups.