Tetraspanin |
CD9, CD37, CD63, CD53, CD81,CD82, CD83 |
Biomarker, multidrug resistance |
[143] |
Heat-shock proteins |
HSP70, Hsp84, Hsp90 αBC, HSP20, HSP27 |
Multidrug resistance, immune suppression |
[144-146,67] |
Signal transduction |
Gi2a, Gi3a, Gsa, FRL, Erk2, Fyn, Sh2, phosphatase, RhoA, C, GDI, syntenin, CBL, Catenin, LCK |
Signal transformation |
[71] |
MVB formation |
Alix, TSG 101, Gag |
Cell trafficking, biomarker |
[67] |
Antigen presentation |
MHC I, MHC II, CD86 |
Immune system regulation |
[72] |
Adhesion molecules/targeting proteins |
CD146, CD166, ICAM-1, ALCAM, MAC-1, Integrin α chain, Integrin α
4 ß1, LFA-3, CD53, CD326, CD11a, 11b, 11c, MFG-E8/lactadherin, CD171, CLDN3 |
Intercellular communication |
[73,146] |
Cytoskeletal proteins |
Talin, CAP1, ezrin, tubulin, cofilin, actin, moesin, rodixin, advillin, vimentin |
Tumorigenesis, immune system regulation |
[147] |
Membrane transport and fusion |
AP-1, Arp2/3, SNAP, syntaxin, dynamin, Rab5, 7, Rap1B, RabGDI, annexins (I, II, IV, V, VI), epidermal growth factor receptor (EGFR) |
Biogenesis, cell transportation |
[148] |
Enzymes |
ATP citrate lyase, ATPase, glucose 6-phosphate isomerase, peroxiredoxin 1, Asp, amino-transferase, aldehyde reductase, fatty acid synthase, pyruvate kinase, glucose 6-phosphate isomerase, ATP citrate, lyase, ATPase, fatty acid synthase (FASN) Thioredoxine peroxidase and alix |
Metabolism, cell signaling |
[149,71] |
Anti-apoptosis proteins |
Cell progression and angiogenesis, multidrug resistance |
[69] |
Domain proteins |
Proliferation cell nuclear antigen (PCNA) |
Proliferation, angiogenesis |
[73] |