Figure 4.

Id2 influences sorafenib-induced HCC cell apoptosis. A. Id2-knockdown Huh7 cells or control cells were treated with sorafenib (0, 15, 30 µM) for 24 h, and apoptotic cells were assessed by flow cytometry. B. Id2-overexpressing SMMC-7721 cells or control cells were treated with sorafenib (0, 15, 30 µM) for 24 h, and apoptotic cells were assessed by flow cytometry. C. Cleaved caspase 3 and Id2 were detected by western blotting in HCC cells with the overexpression or knockdown of Id2. **P<0.01.