Table 1.
Covariate | Level | N stage | ||||
---|---|---|---|---|---|---|
| ||||||
NX (n = 834) | N0 (n = 73256) | p value | N1 (n = 18387) | p value | ||
Age | 45.37 ± 19.86 | 50.33 ± 14.85 | < 0.001 | 45.55 ± 16.33 | 0.001 | |
Sex | Female (%) | 628 (75.3) | 58199 (79.4) | 0.003 | 12476 (67.9) | < 0.001 |
Male (%) | 206 (24.7) | 10566 (20.6) | 5911 (32.1) | |||
Race | White (%) | 587 (75.4) | 59742 (82.5) | < 0.001 | 15209 (83.7) | < 0.001 |
Black (%) | 78 (10.0) | 5396 (7.5) | 570 (3.1) | |||
Other (%) | 114 (14.6) | 7226 (10.0) | 2400 (13.2) | |||
Histology type | PTC (%) | 708 (84.9) | 67950 (92.8) | < 0.001 | 18184 (98.9) | < 0.001 |
Other (%) | 126 (15.1) | 5306 (7.2) | 203 (1.1) | |||
T-stage | T1 (%) | 164 (35.0) | 48296 (66.6) | < 0.001 | 6618 (37.0) | < 0.001 |
T2 (%) | 83 (17.7) | 12370 (17.1) | 2865 (16.0) | |||
T3 (%) | 77 (16.5) | 10479 (14.5) | 6529 (36.5) | |||
T4 (%) | 144 (30.8) | 1353 (1.9) | 1869 (10.5) | |||
M-stage | M0 (%) | 656 (78.7) | 72697 (99.2) | < 0.001 | 17737 (96.5) | < 0.001 |
M1 (%) | 178 (21.3) | 559 (0.8) | 650 (3.5) | |||
Multifocality | No (%) | 316 (64.5) | 46165 (64.1) | 0.849 | 7857 (44.2) | < 0.001 |
Yes (%) | 174 (35.5) | 25883 (35.9) | 9924 (55.8) | |||
Extension | No (%) | 328 (65.7) | 66029 (90.5) | < 0.001 | 10783 (60.2) | 0.012 |
Yes (%) | 171 (34.3) | 6965 (9.5) | 7141 (39.8) | |||
Radiation | None or refused | 534 (67.1) | 41037 (57.2) | < 0.001 | 4409 (24.7) | < 0.001 |
Radiation beam or radiation implants (%) | 55 (6.9) | 1063 (1.5) | 599 (3.3) | |||
Radiosotopes or radiation beam and isotopes/implants (%) | 207 (26.0) | 29646 (41.3) | 12858 (72.0) | |||
Surgery | Lobectomy (%) | 106 (22.4) | 12790 (17.9) | 0.021 | 420 (2.3) | < 0.001 |
Subtotal or near-total thyroidectomy (%) | 24 (5.1) | 3028 (4.2) | 340 (1.9) | |||
Total thyroidectomy (%) | 344 (72.5) | 55665 (77.9) | 17125 (95.8) | |||
Survival months | 38.41 ± 35.66 | 49.92 ± 33.82 | < 0.001 | 44.68 ± 32.16 | < 0.001 |
PTC: papillary thyroid cancer.