Effect of TPX, ERB and combination of TPX+ERB treatment on expression of proteins p21, caspase-3, β-Catenin, PCNA, COX-2, 5-LOX and Bcl2. The combination of TPX+ERB significantly increased expression of p21 and caspase-3, whereas the expression of β-Catenin, PCNA, COX-2, 5-LOX and Bcl2 decreased significantly compared to control. Actin was used as loading standard. (The data presented is mean ± SEM, *P<0.05 and **P<0.01 compared control).