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. 2018 Dec 6;11:447. doi: 10.3389/fnmol.2018.00447

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Copyright © 2018 Yang, Peng, Wu, Li, Wang, Luo and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Huntington-interacting protein 1-related protein (HIP1R) co-localizes with actin during neurite initiation. (A) Expression of HIP1R in cultured hippocampal neurons at different time points. (B) Representative images of HIP1R expression in cultured hippocampal neurons. HIP1R (gray), phalloidin (red) and MAP2 (green). Open arrowhead, neurite initiation stage 1a; filled arrowhead, stage 1b; filled arrow, stage 2. Scale bar, 10 μm. (C) Representative analysis of fluorescence intensity distributions of HIP1R and F-actin in neuron. Line scan method was used to detect the intensities of fluorescent signals (right panel) along the red line in the example neuron (left panel).