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. 2017 Apr 26;19(6):1183–1202. doi: 10.1093/bib/bbx041

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© The Author 2017. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Comparison of novel predicted interactions. (A) Overlap of the first percentile predictions in five networks for unsupervised methods, considering the representative method of each class: MFb (MF-based), Jac (projection-based) and CJC (LCP-based). (B) Overlap of the nodes (drugs and targets) involved in the first percentile predictions for the unsupervised methods. (C) Overlap of the first percentile predictions in four networks for supervised and LCP-based methods, considering the representative method of each class: BLMd (supervised), GRMFdt (supervised) and CJC (LCP-based). (D) Overlap of the nodes (drugs and targets) involved in the first percentile predictions for the previous methods.