Table 3.
History of bleeding events.
| Total (N=3,455) | DVT only (n=2,056) | PE ± DVT (n=1,399) | p-value PE ± DVT vs. DVT only | |
|---|---|---|---|---|
| Total bleeding | 133/3451 (3.9) | 74/2053 (3.6) | 59/1398 (4.2) | 0.3562 |
| Major bleeding | 36/133 (27.1) | 19/74 (25.7) | 17/59 (28.8) | |
| CRNM bleeding | 68/133 (51.1) | 36/74 (48.6) | 32/59 (54.2) | |
| Nuisance bleeding | 29/133 (21.8) | 19/74 (25.7) | 10/59 (16.9) | |
| Gastrointestinal * | 46/133 (34.6) | 28/74 (37.8) | 18/59 (30.5) | 0.3773 |
| Major bleeding | 12/46 (26.1) | 6/28 (21.4) | 6/18 (33.3) | |
| CRNM bleeding | 23/46 (50.0) | 14/28 (50.0) | 9/18 (50.0) | |
| Nuisance bleeding | 11/46 (23.9) | 8/28 (28.6) | 3/18 (16.7) | |
| Intracerebral | 17/133 (12.8) | 6/74 (8.1) | 11/59 (18.6) | 0.0706 |
| Other | 72/133 (54.1) | 42/74 (56.8) | 30/59 (50.8) | 0.4968 |
| Major bleeding | 16/72 (22.2) | 11/42 (26.2) | 5/30 (16.7) | |
| CRNM bleeding | 37/72 (51.4) | 19/42 (45.2) | 18/30 (60.0) | |
| Nuisance bleeding | 19/72 (26.4) | 12/42 (28.6) | 7/30 (23.3) |
All data are given as n/N (%). Multiple reasons could be given for a bleeding event. CRNM, clinically relevant non-major; DVT, deep vein thrombosis; PE, pulmonary embolism;
* patients may have had major and/or CNRM and/or nuisance bleeding.