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. 2018 Dec 7;14:1176934318810990. doi: 10.1177/1176934318810990

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Hrd1 RING domain is conserved in different fungi. (A) Sequence alignment of the Hrd1 RING domains in different fungi. Red shows sequence identity, blue shows sequence is conserved over 75% species, whereas purple displays only over a half, and the consensus exhibited the conserved amino acids. (B) Sequence logo diagram shows Hrd1 RING domain ortholog in different fungi. The alignment was performed using the ClustalX software. The logo was built using the WebLogo software (http://weblogo.berkeley.edu/logo.cgi).