Figure 3.

Voltage-dependent potassium (K_V) current properties. (A) Representative K_V current traces recorded from mid- to high-frequency NM and NMc neurons, in response to membrane voltages from −100 mV to +20 mV in a step of 5 mV. Arrow points to transient A-type current. (B) Population data showing the amplitude of steady-state K_V current (I_K) as a function of membrane voltage (V_MEMBRANE) for the two neuronal groups. (C) Average percent contribution of K_V3-, K_V1-, and K_V2-mediated currents to total K_V current at the membrane voltage of +20 mV. (D and F) Representative membrane responses recorded from mid- to high-frequency NM (D) and NMc (F) neurons to sustained current injection. The amplitude of current injection is 500 and 200 pA, respectively. (E and G) Population data showing the differences in active (E) and passive (G) membrane properties between the two neuronal groups. Reliability is a measure of jitter and was defined as the range of peak occurrences of 30 action potentials (APs). Data were adapted from Hong et al^42,43 and Wang et al.¹⁹ Error bar = standard error. NM indicates nucleus magnocellularis; RMP, resting membrane potential; Tau, time constant.