Skip to main content
. 2018 Dec 12;12:1179069518815628. doi: 10.1177/1179069518815628

Figure 4.

Figure 4.

Function of KV1- and KV3-containing channels in NM neurons. (A) Representative membrane responses recorded from a mid- to high-frequency NM neuron to sustained current injection (100 ms) in control and with bath application of dendrotoxin (DTx, 0.1 μM). DTx blocks KV1-containing channels. The amplitude of current injection is 440 pA in control and 60 pA with DTx. (B) Representative APs (normalized) recorded from a mid- to high-frequency NM neuron in control and with bath application of TEA (1 mM). TEA mainly blocks KV3-containing channels. (C) Representative membrane responses recorded from a mid- to high-frequency NM neuron to square pulse trains of 200 Hz in control and with TEA. Asterisks denote AP failures. (D) Population data showing the difference in firing probability to 200 Hz input. Firing probability was calculated as the number of APs divided by the number of square pulses. Error bar = standard error. Data were adapted from Hong et al.42,50 APs indicates action potentials; Cont, control; NM, nucleus magnocellularis; TEA, tetraethylammonium.