Table 1.

Inclusion and exclusion criteria

Inclusion Criteria

Adult 21 or over diagnosed > 1 yr. ago with multiple sclerosis

Able to read and understand informed consent form and study instructions

Waist and leg circumference and lower extremity lengths appropriate for a comfortable and safe fit in the Keeogo device

Able to walk 25 m without stopping, without human assistance, using assistive devices and ankle-foot-orthoses, as necessary

Can complete a 10 step stair test

Score > 23 on the Mini-Mental State Examination

Modified Ashworth Score (MAS) < 3 for knee or hip, and < 3 for ankle if no AFO is used

Recent (< 12mo) Kurtz Expanded Disability Status Score (EDSS) evaluation on record, with EDSS ≤6.5

Exclusion Criteria

Legally blind

Pregnant or lactating

Skin condition that contraindicates use of orthotics or support braces

Recent (< 6 mo) lower-body hospitalizations or active treatments due a joint, muscle, bone, nerve or vascular injury or condition

Scheduled for major surgery within next 4 months

Lower-extremity amputation above or below the knee

Have uncontrolled hypertension

Recent (< 1 year) heart attack

Have uncontrolled diabetes

Diagnosed with other health condition(s) that affect mobility and balance, including chronic obstructive pulmonary disease; peripheral arterial disease; vestibular disorders; cerebellar disease; cerebral palsy; muscular dystrophy; spinal cord injury; stroke or other brain injury.