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. 2018 Dec 12;15:58. doi: 10.1186/s12970-018-0264-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — CONSORT diagram for Study Participants. A total of 485 participants were screened. Healthy active young men and women were randomly assigned to one of two treatments, 0 PLA or 900 mg/day PSE (Total randomized N = 142; N = 69 (PLA), N = 73 (PSE)). A total of 54 and 52 subjects completed the trial in the PLA and 900 mg/day PSE groups, respectively. Abbreviations: PSE, proprietary spearmint extract; PLA, placebo; AE, adverse event