Table 1.

Correlations between GRINA expression and clinicopathological parameters in 569 gastric cancer patients

Clinicopathological variables	GRINA Expression		P Value
	Low(n = 268)	High(n = 301)
Age
< 60	123	176
≥ 60	145	125	0.06
Sex
Male	190	201
Female	78	100	0.595
Histological differentiation
Well	88	72
Moderate/Poor	180	229	0.04*
Depth of tumor (pT)
T1	54	32
T2	42	38
T3	62	89
T4	110	152	0.027*
Nodal stage (pN)
N0	120	96
N1	49	56
N2	48	66
N3	51	83	0.03*
Distant metastasis (pM)
M0	267	299
M1	1	2	0.032*
Blood vessel invasion
Negative	236	239
Positive	32	62	0.04*
Perineuronal invasion
Negative	248	252
Positive	20	49	0.005**

*P < 0.05 statistically significant difference