Table 2.
Reporting of clinical trial endpoints between clinical trial protocols and clinical trial registries
| Endpoint Reporting | Trials | (%) | Endpoints | (%) |
|---|---|---|---|---|
| Clinical trial protocols with primary endpoints | 71 | 75 | ||
| Primary Endpoint Discrepancies | 4 | (6) | 4 | (5) |
| Clinical trial protocols with secondary endpoints | 71 | 507 | ||
| Secondary Endpoint Discrepancies | 45 | (63) | 113 | (22) |
| Secondary endpoints absent from registry | 36 | (51) | 84 | (17) |
| Included in published report | 27 | (38) | 48 | (9) |
| Secondary endpoints absent from protocol | 19 | (27) | 29 | (6) |
| Included in published report | 7 | (10) | 9 | (2) |
| Present in non-endpoint section of protocol | 11 | (15) | 14 | (3) |
| Clinical trial protocols with exploratory endpoints | 28 | 96 | ||
| Exploratory endpoints absent from registry | 25 | (89) | 89 | (93) |