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. 2018 Dec 12;19:86. doi: 10.1186/s40360-018-0274-6

Table 1.

Characteristics of studies describing the resistance profile of clinical relevant bacterial isolates against ciprofloxacin

Study ID Quality score Year (pub) Study Area Study Design Population (Clinical features) Source of sample Bacterial Category Type of isolates Number of isolates No of resistant (%)
Abamecha et al. [35] 8.5 2015 JUSH CS Hospitalized patients Stool Gram + Ve E. faecalis 114 57 50.00
Abera et al. [51] 9 2016 FHRH CS In/outpatients with infections Urine and Blood Gram -Ve E. coli 122 49 40.16
K. Pneumoniae 49 28 57.14
P. mirabilis 29 10 34.48
Alemseged et al. [43] 8 2015 ARH and MHC, Mekele CS Pregnant women Vaginal swabs Gram + Ve GBS 19 1 5.26
Ali et al. [78] 8.5 2016 Gambella hospital CS STI suspected patients Urethral or endo-cervical swabs Gram -Ve N. gonorrhoeae 21 6 28.57
Ameya et al. [36] 8 2018 Arba Minch province CS Under five children (diarrhea) Stool Gram -Ve Salmonela 21 0 0.00
Shigella 8 0 0.00
Denboba et al. [46] 7.5 2016 DRHRL CS (R) Patients with Otitis media Ear discharges Gram + Ve S. auerus 102 1 0.98
Gram -Ve Pseudomonas spp 134 13 9.70
Proteus spp 114 8 7.02
K. pneumoniae 9 0 0.00
E. coli 69 6 8.70
Assefa et al. [55] 8 2015 UoGH CS Dacryocystitis patients Nasolacrim al discharge Gram + Ve S. auerus 6 0 0.00
CoNS 9 4 44.44
Ayelign et al. [20] 8.5 2018 UoGH CS Pediatric patients with UTI Urine specimens Gram + Ve S. auerus 8 0 0.00
Gram -Ve E. coli 45 8 17.78
Pseudomonas spp 8 1 12.50
Bekele et al. [21] 7 2015 JUSH CS Catheterized patients Urine samples (Catheter) Gram -Ve Pseudomonas spp 36 0 0.00
Bitew et al. [22] 8.5 2017 Arsho AML, AA CS Patients with UTI Urine Gram + Ve S. auerus 9 3 33.33
E. faecalis 14 1 7.14
Gram -Ve E. coli 135 68 50.37
K. pneumoniae 18 3 16.67
Deribe et al. [23] 6.5 2017 Bahir Dar Regional HRLC CS (R) Patient with presumptive UTI Urine Gram + Ve S. auerus 9 3 33.33
Gram -Ve E. coli 64 41 64.06
K. pneumoniae 19 4 21.05
Pseudomonas spp 8 0 0.00
Proteus spp 6 4 66.67
Dereje et al. [24] 8.5 2017 Hamlin fistula hospital, AA CS Fistula patients (UTI) Urine Gram -Ve E. coli 65 37 56.92
K. pneumoniae 14 11 78.57
Proteus spp 31 14 45.16
Derese et al. [25] 9.5 2016 DRH CS Pregnant women with UTI Urine Gram + Ve CoNS 5 1 20.00
Gram -Ve E. coli 9 1 11.11
Dessie et al. [50] 9 2016 Selected referral hospitals, AA CS Surgical site infected patients Wound swabs Gram + Ve S. auerus 19 3 15.79
Gram -Ve E. coli 24 16 66.67
K. pneumoniae 10 2 20.00
Pseudomonas spp 6 2 33.33
Eshetie et al. [26] 9.5 2015 UoGH CS Patients with UTI Urine Gram -Ve E. coli 104 1 0.96
K. pneumoniae 28 3 10.71
Gebrekidan et al. [37] 7.5 2015 Mekele hospital CS Outpatients with acute diarrhea Stool Gram -Ve Shigella 15 1 6.67
Teweldemedihin [40] 8 2017 Quiha Ophthalmic Hospital CS Patients with ocular infections Ocular specimens Gram + Ve S. auerus 40 5 12.50
CoNS 31 3 9.68
E. faecalis 8 1 12.50
K. Pneumonia 7 1 14.29
Pseudomonas spp 21 4 19.05
E. coli 15 1 6.67
Getahun et al. [41] 10 2017 UoGH CS Patients with ocular infections Ocular samples/ external Gram + Ve S. auerus 96 7 7.29
CoNS 64 7 10.94
Gram -2015Ve E. coli 6 1 16.67
K. pneumoniae 9 2 22.22
Gezmu et al. [27] 6 2016 Arba Minch Hospital CS Patients with UTI Urine Gram + Ve S. auerus 10 3 30.00
Gram -Ve E. coli 20 4 20.00
K. pneumoniae 8 2 25.00
Hailu et al. [34] 8 2016 Bahir Dar Reg HRLC CS Febrile patients Blood Gram + Ve S. auerus 50 10 20.00
CoNS 35 3 8.57
Gram -Ve E. coli 19 5 26.32
K. pneumoniae 35 10 28.57
Pseudomonas spp 15 2 13.33
Hailu et al. [49] 7.5 2016 Bahir Dar Regional HRLC CS (R) Patiets with infected wounds wound swab Gram + Ve S. auerus 67 5 7.46
S. pyogens 20 1 5.00
Gram -Ve E. coli 33 15 45.45
K. Pneumonia 20 4 20.00
Pseudomonas spp 26 5 19.23
Proteus spp 22 5 22.73
Hailu et al. [47] 7.5 2016 Bahir Dar Regional HRLC CS (R) Patients with ear infections Ear discharges Gram + Ve S. auerus 78 0 0.00
CoNS 34 0 0.00
S .pneumonia 7 0 0.00
Gram -Ve E. coli 7 1 14.29
K. Pneumoniae 10 1 10.00
Pseudomonas spp 88 7 7.95
Proteus spp 65 3 4.62
Kumalo et al. [30] 7 2016 JUSH CS Sepsis patients Blood Gram + Ve S. auerus 6 1 16.67
Lamboro et al. [38] 8.5 2016 JUSH CS Outpatients with diarrhea Stool Gram -Ve Salmonella 19 0 0.00
Mengist et al. [44] 7 2016 JUSH CS Pregnant women Anorectal and Vaginal Gram + Ve GBS 31 3 9.68
Mitku [28] 6.5 2017 DRHRL CS (R) Outpatients with UTI Urine Gram -Ve E. coli 25 2 8.00
K. Pneumoniae 7 1 14.29
Proteus spp 6 1 16.67
Mulu et al. [52] 8.5 2017 DMRH CS (R) Any patients with infection Non specific/ all types Gram + Ve S. auerus 13 6 46.15
Gram -Ve E. coli 22 4 18.18
Pseudomonas spp 17 6 35.29
Salmonella 16 4 25.00
N. gonorrheae 8 13 61.53
Negussie et al. [31] 6.5 2015 Selected hospitals, AA CS Septicemia suspected children Blood Gram + Ve S. auerus 13 4 30.77
CoNS 11 2 18.18
Gram -Ve K. pneumoniae 9 4 44.44
Nigussie and Amsalu [29] 7.5 201 HURH CS Diabetic patients Urine Gram + Ve S. auerus 6 3 50.00
CoNS 8 4 50.00
Gram -Ve E. coli 11 2 18.18
Regassa et al. [53] 8 2015 JUSH CS CAP paients Sputum and Blood Gram + Ve S. auerus 16 5 31.25
Gram -Ve Pseudomonas spp 10 2 20.00
K. pneumoniae 8 0 0.00
Sahile et al. [54] 6 2016 JUSH CS Patients with surgical and gynecologic wound Urine and wound swab Gram + Ve S. auerus 22 13 59.09
CoNS 21 16 76.19
Gram -Ve E. coli 9 4 44.44
Pseudomonas spp 8 4 50.00
Proteus spp 7 3 42.86
Shiferaw et al. [42] 8.5 2015 BoruMeda Hospital CS Patients with ex-ocular infections External ocular specimens Gram + Ve S. auerus 21 2 9.52
CoNS 51 4 7.84
S. pneumoniae 10 2 20.00
S. pyogens 6 0 0.00
Terfasa and Jida [39] 8 2018 Nekemte referral hospital CS Diarrheal patients Stool Gram -Ve Salmonella 30 2 6.67
Shigella 9 0 0.00
Wasihun et al. [32] 8 2015 Mekelle hospital CS Febrile patients Blood Gram + Ve S. auerus 54 21 38.89
CoNS 44 11 25.00
Gram -Ve E. coli 16 1 6.25
Salmonela 8 4 50.00
Wasihun et al. [33] 8.5 2015 Mekelle hospial CS Febrile patients Blood Gram + Ve S. auerus 41 18 43.90
CoNS 39 10 25.64
S. pyogens 6 1 16.67
Gram -Ve E. coli 12 1 8.33
Salmonella 8 1 12.50
Wasihun and Zemene [48] 8 2015 ARH CS Patients with otitis media Ear discharges Gram + Ve S. auerus 46 10 21.74
CoNS 17 9 52.94
S. pneumonia 15 3 20.00
S. pyogens 16 3 18.75
Gram -Ve Proteus spp 39 0 0.00
Pseudomonas spp 27 10 37.04
K. pneumoniae 18 2 11.11
E. coli 6 1 16.67
Mulu et al. [45] 7 2015 FHRH CS Women with vaginal infections Vaginal swabs Gram + Ve S. auerus 15 3 20.00
Gram -Ve E. coli 6 2 33.33
Pseudomonas spp 7 0 0.00

Abbreviations: CoNS coagulase negative Staphylococci, CS cross-sectional, R retrospective, HURH Hawassa University Referral Hospital, UoGH University of Gondar Hospital; JUSH Jimma University Specialized Hospital, DRHRL Dessie Regional Health Research laboratory, STI sexually transmitted diseases, UTI Urinary tract infections, ARH Ayder Referral Hospital, GBS Group B Streptococci, FHRH Felege Hiwot Referral Hospital, DMRH Debre Markos Referral Hospital, CAP Community Acquired Pneumonia