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. 2017 Nov 28;117(7):1348–1357. doi: 10.1160/TH17-01-0030

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This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Figure 3:
KD
-based simulation of an equilibrium state in the presence of the standard plasma concentrations of FIX and FX — . Concentrations of FIX–emicizumab–FX ternary complex (A), and the percent ratio of monomer, binary complex, and ternary complex of FIX to total FIX (B) or those of FX to total FX (C), which were simulated on the basis of the K _D values at varied concentrations of emicizumab.