Skip to main content
. 2018 Dec 6;24:8812–8821. doi: 10.12659/MSM.911972

Figure 1.

Figure 1

Frequent downregulation of miR-29abc in MTX-resistant osteosarcoma cells and tissues. (A) IC50 value for MTX in MG-63 and MG-63/MTX cells determined using CCK-8 assay. (B) IC50 value for MTX in U2OS and U2OS/MTX cells determined using CCK-8 assay. (C) Relative expression levels of miR-29abc in MG-63 and MG-63/MTX cells assessed by qRT-PCR analysis. (D) Relative expression levels of miR-29abc in U2OS and U2OS/MTX cells assessed by qRT-PCR analysis. (E–G) Relative expression levels of miR-29abc in 18 poor-response osteosarcoma tissues (<90% tumor necrosis after chemotherapy) and 18 stage-matched good-response osteosarcoma tissues (≥90% tumor necrosis after chemotherapy) analyzed by qRT-PCR. ** P<0.01.