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. 2018 Dec 6;24:8831–8839. doi: 10.12659/MSM.910932

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© Med Sci Monit, 2018

This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

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LINC01118 enhanced invasion and migration in EOC cells. (A) Wound healing assay in SKOV3 cells with LINC01118 overexpression plasmid compared with negative control group. (B) The wound healing percentage of plasmid group was significantly higher than in the control group. (C) Wound healing results in SKOV3-TR30 cells with siRNA-LINC01118 compared with NC. (D) Downregulation of LINC01118 significantly inhibited the wound healing. (E, F) The migration ability was significantly enhanced compared with the control group when LINC01118 was overexpressed in SKOV3. (G, H) The invasion was promoted compared with the control group when LINC01118 was overexpressed in SKOV3. (I, J) The migration was decreased compared with NC group in SKOV3-TR30. (K, L) The invasion ability was decreased compared with NC group in SKOV3-TR30. * P<0.05 and ** P<0.01.