Table 1.

Grading of Recommendations Assessment, Development and Evaluation

Grade recommendation	Interpretation
High quality	Where further research is unlikely to change confidence in the estimate of effect
Moderate quality	Where further research is likely to impact on confidence in the estimate of effect
Low quality	Where further research is very likely to have an important impact on confidence in the effect size and is likely to change the estimate
Very low quality	Where great uncertainty about the estimate exists