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. Author manuscript; available in PMC: 2018 Dec 13.
Published in final edited form as: Cell Rep. 2018 Oct 16;25(3):726–736.e7. doi: 10.1016/j.celrep.2018.09.041

Figure 2. Rbm17 Deletion in Adult Mice Is Lethal, and Knockdown Alters Levels of Its Interactors.

Figure 2.

(A) Representative western blots (left) and protein-level quantifications (right) of the six validated interactors of RBM17 in Rbm17 adult conditional knockout (aCKO) mice versus control littermates (n = 6 aCKO and n = 7 control littermates). The area boxed by a dashed line indicates an empty well.

(B) Representative western blots (left) and protein-level quantifications (right) of the six validated interactors of RBM17 in HEK293T treated with siRBM17 or siScramble (n = 6–18 replicates/siRNA). All data were normalized to mouse or human Vinculin (VCL), used here as loading control.

For both panels, bars represent mean ± SEM; p value was calculated by two-tailed Student’s t test, and significance was set at p < 0.05. The 98 kDa mark indicates the relative position of the two bands detected for DHX15 and does not concern any of the other proteins. See also Figure S2.