Plasma haptoglobin concentrations in feedlot receiving steers supplemented or not (no immunomodulatory ingredient supplementation during feedlot receiving [CON]; n = 6) with 1) 2 oral capsules of Stocker Immune Primer on d 0 + 15 g/steer daily (as-fed basis) of Stocker Preconditioned Premix (Ramaekers Nutrition, Santa Cruz, CA; n = 6) from d 7 to 30 (IPF) or 2) supplementation with OmniGen-AF (OMN; 22 g/steer daily, as-fed basis, from d 0 to 30; Phibro Animal Health Corp., Teaneck, NJ; n = 6). A treatment × day interaction was detected (P ≤ 0.05). Blood samples collected on d 0 were a significant covariate (P = 0.02) but did not differ among treatments (0.21, 0.25, and 0.28 mg/mL [SEM 0.04] in CON, IPF, and OMN steers, respectively). Within day, letters indicate the following treatment differences: aIPF vs. CON (P ≤ 0.10), bOMN vs. CON (P = 0.10), and cOMN vs. IPF (P = 0.09).