Table 2. Association between baseline use of statins and incident knee osteoarthritis outcomes.
| Number of events/number of participants |
Full-adjusted model1 (RR, 95%CI) |
p-value | Propensity-score model2 (RR, 95%CI) |
p-value | |
|---|---|---|---|---|---|
| Pain worsening | 3,678/4,448 (=82.7%) | 0.97 (0.93-1.02) | 0.23 | 0.97 (0.93-1.02) | 0.24 |
| ROA | 431/1,936 (=22.2%) | 1.31 (0.83-2.09) | 0.25 | 1.41 (0.86-2.32) | 0.17 |
| SxOA | 201/3,364 (=5.9%) | 0.97 (0.87-1.09) | 0.63 | 0.98 (0.88-1.11) | 0.78 |
Notes:
All the data are presented as relative risk with their 95% confidence intervals.
1
Fully adjusted model included as covariates: age (as continuous); sex; race (whites vs. others); education (degree vs. others); body mass index (as continuous); yearly income (categorized as ≥ or < 50,000$ and missing data); CES-D: Center for Epidemiologic Studies Depression Scale; smoking habits (current and previous vs. others); Physical Activity Scale for Elderly score (as continuous); Charlson co-morbidity index; number of medications used; use of statins during follow-up period; maximum knee extension.
2
Propensity score model included as covariate the propensity score divided into quintiles.
Abbreviations: CI: confidence intervals; RR: relative risk.