. 2018 Dec 3;7:e39981. doi: 10.7554/eLife.39981

Table 1. Enrichment for Irf7 binding site DNA motifs in up-regulated 12 week old Atxn1^154Q/2Q inferior olive genes.

Brain region	Motif occurrence	Down-Regulated	Shuffled	p-value	q-value
Inferior Olive	Present	32	26	0.468	0.123
Inferior Olive	Absent	128	134	0.468	0.123
Brain Region	Motif Occurrence	Up-Regulated	Shuffled	p-value	q-value
Inferior Olive	Present	27	2	8.8e-9	9.2e-9
Inferior Olive	Absent	17	42	8.8e-9	9.2e-9

FDR p-value calculated using the two-stage linear step-up procedure of Benjamini, Krieger, and Yekutieli (Q 5%).

Table 1. Enrichment for Irf7 binding site DNA motifs in up-regulated 12 week old Atxn1154Q/2Q inferior olive genes.