Fig 1. Altered mRNA expression of specific calcium release activated calcium (CRACs) channel and voltage-gated calcium channel (Ca_v) subunits in PBMCs from non-pregnant controls and pregnant women.

Data from each group is presented as scatter dot plot (°) or box and whiskers plot with median and whiskers plotted by Tukey method to determine outliers (• - above or below the whiskers). Ca_V1.1 subunit mRNA was not detected in any sample. Statistical analysis was performed by excluding outliers depending on normality distribution of the data and only the subunits with statistically significant differences are mentioned below. One-Way ANOVA with Bonferroni post-hoc test: ORAI1, df = 48, p = 0.003; Kruskal–Wallis ANOVA on ranks with Dunn’s post hoc test: ORAI2, H_{(1, 46)} = 28.5, p < 0.001; ORAI3, H_{(1, 54)} = 37.2, p < 0.001; STIM1, H_{(1, 58)} = 18.3, p < 0.001; STIM2, H_{(1, 58)} = 32.5, p < 0.001; Ca_V2.1, H_{(1, 48)} = 13.1, p < 0.001; Ca_V2.3, H_{(1, 49)} = 22.1, p < 0.001; Ca_V3.2, H_{(1, 31)} = 17.7, p < 0.001. ** p < 0.01, *** p < 0.001.