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letter

. 2018 Nov 12;2(6):567–579. doi: 10.1002/evl3.89

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© 2018 The Author(s). Evolution Letters published by Wiley Periodicals, Inc. on behalf of Society for the Study of Evolution (SSE) and European Society for Evolutionary Biology (ESEB).

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Genes of the Toll and Imd pathways represent longevity candidates. Overview of the Toll and Imd pathways, the two major pathways regulating the humoral innate immune response against fungi and gram‐positive bacteria (Toll) and gram‐negative bacteria (Imd). Among our longevity candidates we found an enrichment of immunity‐related genes (enrichment of GO terms associated with “antifungal peptides”). Longevity candidate genes identified in the Toll and Imd pathways are shown in red. For additional immunity‐related candidate genes see Table S4.