APPENDIX 1A.
Control group descriptive statistics for PANSS-Ru by age
| ALL GROUPS | AGE GROUP | n | MEAN | 95% CONFIDENCE INTERVAL FOR MEAN | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LOWER BOUND | UPPER BOUND | MEDIAN | VARIANCE | SD | MIN | MAX | SKEWNESS | KURTOSIS | STD.ERROR | ||||
| PANSS-Ru Positive Symptoms | ≤25 years | 40 | 11.62 | 10.62 | 12.62 | 12 | 4.848 | 2.202 | 7 | 15 | -0.332 | -0.504 | 0.48 |
| 26–35 years | 43 | 12.4 | 11.45 | 13.34 | 12 | 9.435 | 3.072 | 7 | 18 | 0.279 | -1.058 | 0.468 | |
| 36–45 years | 37 | 12.52 | 11.45 | 13.58 | 12 | 7.259 | 2.694 | 9 | 18 | 0.328 | -0.896 | 0.519 | |
| 46–55 years | 28 | 13.33 | 11.61 | 15.06 | 13 | 12 | 3.464 | 9 | 22 | 0.945 | 1.095 | 0.816 | |
| ≥56 years | 20 | 13.08 | 10.81 | 15.36 | 12.5 | 12.811 | 3.579 | 8 | 20 | 0.604 | -0.229 | 1.033 | |
| PANSS-Ru Negative Symptoms | ≤25 years | 40 | 9.86 | 8.9 | 10.82 | 10 | 4.429 | 2.104 | 7 | 16 | 1.026 | 2.349 | 0.459 |
| 26–35 years | 43 | 10.7 | 9.83 | 11.57 | 10 | 7.978 | 2.825 | 7 | 17 | 0.649 | -0.549 | 0.431 | |
| 36–45 years | 37 | 10.7 | 9.39 | 12.01 | 9 | 10.986 | 3.314 | 7 | 19 | 0.938 | 0.025 | 0.638 | |
| 46–55 years | 28 | 11.94 | 10.06 | 13.83 | 12 | 14.408 | 3.796 | 7 | 22 | 0.927 | 1.394 | 0.895 | |
| ≥56 years | 20 | 11.83 | 10.06 | 13.61 | 12.5 | 7.788 | 2.791 | 7 | 15 | -0.337 | -1.469 | 0.806 | |
| PANSS-Ru General Psychopathology | ≤25 years | 40 | 26.81 | 23.95 | 29.67 | 26 | 39.362 | 6.274 | 18 | 38 | 0.253 | -1.144 | 1.369 |
| 26–35 years | 43 | 26.23 | 24.39 | 28.07 | 26 | 35.802 | 5.983 | 17 | 42 | 0.639 | 0.052 | 0.912 | |
| 36–45 years | 37 | 26.04 | 23.93 | 28.14 | 26 | 28.268 | 5.317 | 17 | 36 | -0.06 | -0.684 | 1.023 | |
| 46–55 years | 28 | 28.5 | 24.46 | 32.54 | 27.5 | 66.029 | 8.126 | 19 | 44 | 0.529 | -0.957 | 1.915 | |
| ≥56 years | 20 | 29.17 | 24.4 | 33.94 | 29.5 | 56.333 | 7.506 | 17 | 41 | -0.163 | -0.494 | 2.167 | |
| PANSS-Ru Total | ≤25 years | 40 | 48.29 | 44.61 | 51.96 | 49 | 65.314 | 8.082 | 34 | 61 | -0.306 | -0.981 | 1.764 |
| 26–35 years | 43 | 49.33 | 46.35 | 52.3 | 49 | 93.177 | 9.653 | 36 | 77 | 0.71 | 0.279 | 1.472 | |
| 36–45 years | 37 | 49.26 | 46.02 | 52.5 | 51 | 67.046 | 8.188 | 34 | 66 | -0.159 | -0.419 | 1.576 | |
| 46–55 years | 28 | 53.78 | 47.4 | 60.15 | 52.5 | 164.418 | 12.823 | 37 | 82 | 0.516 | -0.492 | 3.022 | |
| ≥56 years | 20 | 54.08 | 46.87 | 61.3 | 55.5 | 128.992 | 11.357 | 36 | 75 | -0.002 | -0.16 | 3.279 | |
| CGI-S | ≤25 years | 40 | 1.33 | 1.11 | 1.55 | 1 | 0.233 | 0.483 | 1 | 2 | 0.763 | -1.579 | 0.105 |
| 26–35 years | 43 | 1.37 | 1.12 | 1.62 | 1 | 0.668 | 0.817 | 1 | 5 | 3.042 | 10.506 | 0.125 | |
| 36–45 years | 37 | 1.22 | 0.97 | 1.48 | 1 | 0.41 | 0.641 | 1 | 4 | 3.571 | 14.095 | 0.123 | |
| 46–55 years | 28 | 1.44 | 1.14 | 1.75 | 1 | 0.379 | 0.616 | 1 | 3 | 1.085 | 0.387 | 0.145 | |
| ≥56 years | 20 | 1.25 | 0.96 | 1.54 | 1 | 0.205 | 0.452 | 1 | 2 | 1.327 | -0.326 | 0.131 | |
| PANSS-Ru Marder Positive | ≤25 years | 40 | 13.147 | 12.318 | 13.976 | 13 | 5.644 | 2.37579 | 8 | 18 | 0.146 | 0.097 | N/A |
| 26–35 years | 43 | 12.833 | 12.106 | 13.559 | 12 | 7.085 | 2.66175 | 9 | 22 | 1.264 | 2.686 | N/A | |
| 36–45 years | 37 | 13.2 | 12.284 | 14.115 | 13 | 7.106 | 2.66569 | 8 | 20 | 0.583 | 0.384 | N/A | |
| 46–55 years | 28 | 14.416 | 12.76 | 16.072 | 14 | 15.384 | 3.92225 | 9 | 25 | 1.305 | 2.198 | N/A | |
| ≥56 years | 20 | 13.714 | 12.123 | 15.305 | 13 | 12.214 | 3.49489 | 9 | 22 | 0.955 | 0.184 | N/A | |
| PANSS-Ru Marder Negative | ≤25 years | 40 | 8.8529 | 7.9849 | 9.721 | 8.5 | 6.190 | 2.48794 | 7 | 17 | 1.834 | 3.719 | N/A |
| 26–35 years | 43 | 9.9630 | 9.1983 | 10.727 | 9 | 7.848 | 2.80137 | 7 | 20 | 1.152 | 1.707 | N/A | |
| 36–45 years | 37 | 9.3143 | 8.3987 | 10.229 | 9 | 7.104 | 2.66537 | 7 | 17 | 1.025 | 0.381 | N/A | |
| 46–55 years | 28 | 10.208 | 8.8616 | 11.555 | 10 | 10.172 | 3.18937 | 7 | 19 | 0.942 | 0.839 | N/A | |
| ≥56 years | 20 | 9.6667 | 8.3605 | 10.972 | 8 | 8.233 | 2.86938 | 7 | 16 | 0.904 | -0.380 | N/A | |
| PANSS-Ru Marder Anxiety | ≤25 years | 40 | 8.0000 | 7.1584 | 8.8416 | 8.5 | 5.818 | 2.41209 | 4 | 13 | -0.289 | -0.549 | N/A |
| 26–35 years | 43 | 7.4259 | 6.7774 | 8.0744 | 7.5 | 5.645 | 2.37600 | 4 | 13 | 0.284 | -0.410 | N/A | |
| 36–45 years | 37 | 7.4286 | 6.5616 | 8.2955 | 7 | 6.370 | 2.52384 | 4 | 15 | 0.904 | 1.346 | N/A | |
| 46–55 years | 28 | 8.5000 | 7.1589 | 9.8411 | 9 | 10.087 | 3.17600 | 4 | 14 | 0.120 | -1.376 | N/A | |
| ≥56 years | 20 | 7.5714 | 6.4511 | 8.6917 | 7 | 6.057 | 2.46113 | 4 | 13 | 0.572 | 0.077 | N/A | |
| PANSS-Ru Marder Disorganized | ≤25 years | 40 | 10.000 | 9.0320 | 10.968 | 10 | 7.697 | 2.77434 | 7 | 18 | 0.796 | 0.470 | N/A |
| 26–35 years | 43 | 10.388 | 9.6216 | 11.156 | 10 | 7.903 | 2.81114 | 7 | 17 | 0.516 | -0.685 | N/A | |
| 36–45 years | 37 | 10.571 | 9.6132 | 11.529 | 11 | 7.782 | 2.78954 | 7 | 17 | 0.385 | -0.527 | N/A | |
| 46–55 years | 28 | 12.375 | 10.881 | 13.868 | 13 | 12.505 | 3.53630 | 7 | 19 | 0.170 | -0.795 | N/A | |
| ≥56 years | 20 | 11.904 | 10.245 | 13.564 | 12 | 13.290 | 3.64561 | 7 | 21 | 0.796 | 0.507 | N/A | |
| PANSS-Ru Marder Hostility | ≤25 years | 40 | 10.000 | 9.0320 | 10.968 | 10 | 7.697 | 2.77434 | 7 | 18 | 0.796 | 0.470 | N/A |
| 26–35 years | 43 | 10.388 | 9.6216 | 11.156 | 10 | 7.903 | 2.81114 | 7 | 17 | 0.516 | -0.685 | N/A | |
| 36–45 years | 37 | 10.571 | 9.6132 | 11.529 | 11 | 7.782 | 2.78954 | 7 | 17 | 0.385 | -0.527 | N/A | |
| 46–55 years | 28 | 12.375 | 10.881 | 13.868 | 13 | 12.505 | 3.53630 | 7 | 19 | 0.170 | -0.795 | N/A | |
| ≥56 years | 20 | 11.904 | 10.245 | 13.564 | 12 | 13.290 | 3.64561 | 7 | 21 | 0.796 | 0.507 | N/A | |
CGI-S Clinical Global Impressions-Severity; PANSS: Positive and Negative Syndrome Scale; SD: standard deviation; N/A: not applicable