APPENDIX 1B.
Control group average weighted scores with percentiles for the PANSS-Ru by age
| ALL GROUPS | AGE GROUP | PERCENTILES | ||||||
|---|---|---|---|---|---|---|---|---|
| 5 | 10 | 25 | 50 | 75 | 90 | 95 | ||
| PANSS-Ru Positive Symptoms | ≤25 years | 7.1 | 8.2 | 10 | 12 | 13 | 14.8 | 15 |
| 26–35 years | 8.2 | 9 | 10 | 12 | 15 | 17 | 17.8 | |
| 36–45 years | 9 | 9 | 10 | 12 | 15 | 16.2 | 17.6 | |
| 46–55 years | 9 | 9 | 10.75 | 13 | 15 | 19.3 | N/A | |
| ≥56 years | 8 | 8.3 | 11 | 12.5 | 15.75 | 19.4 | N/A | |
| PANSS-Ru Negative Symptoms | ≤25 years | 7 | 7 | 8.5 | 10 | 11 | 12 | 15.6 |
| 26–35 years | 7 | 7 | 9 | 10 | 13 | 15 | 16.6 | |
| 36–45 years | 7 | 7 | 8 | 9 | 13 | 15.4 | 18.2 | |
| 46–55 years | 7 | 7 | 9 | 12 | 14.25 | 16.6 | N/A | |
| ≥56 years | 7 | 7.6 | 9.25 | 12.5 | 14 | 15 | N/A | |
| PANSS-Ru General Psychopathology | ≤25 years | 18 | 18.2 | 21.5 | 26 | 33.5 | 35.8 | 37.8 |
| 26–35 years | 18 | 19 | 20 | 26 | 29 | 35 | 38.6 | |
| 36–45 years | 17 | 17.8 | 22 | 26 | 30 | 34 | 35.2 | |
| 46–55 years | 19 | 19.9 | 20.75 | 27.5 | 34.5 | 42.2 | N/A | |
| ≥56 years | 17 | 17.3 | 23.25 | 29.5 | 34.75 | 40.4 | N/A | |
| PANSS-Ru Total | ≤25 years | 34 | 35 | 41 | 49 | 56 | 57.8 | 60.7 |
| 26–35 years | 36.2 | 37 | 41 | 49 | 54 | 63.8 | 66.8 | |
| 36–45 years | 34.4 | 35.8 | 44 | 51 | 55 | 61 | 64 | |
| 46–55 years | 37 | 38.8 | 42.5 | 52.5 | 64.75 | 70.3 | N/A | |
| ≥56 years | 36 | 36.9 | 43.25 | 55.5 | 59 | 72.6 | N/A | |
| CGI-S | ≤25 years | 1 | 1 | 1 | 1 | 2 | 2 | 2 |
| 26–35 years | 1 | 1 | 1 | 1 | 2 | 2 | 3.6 | |
| 36–45 years | 1 | 1 | 1 | 1 | 1 | 2 | 3.2 | |
| 46–55 years | 1 | 1 | 1 | 1 | 2 | 2.1 | N/A | |
| ≥56 years | 1 | 1 | 1 | 1 | 1.75 | 2 | N/A | |
| PANSS-Ru Marder Positive | ≤25 years | 8.75 | 10 | 12 | 13 | 14 | 17 | 18 |
| 26–35 years | 9 | 10 | 11 | 12 | 14 | 16 | 18.75 | |
| 36–45 years | 8.8 | 10 | 11 | 13 | 15 | 17 | 19.2 | |
| 46–55 years | 9.25 | 10 | 11.5 | 14 | 15.75 | 21 | 24.75 | |
| ≥56 years | 9.1 | 10 | 11 | 13 | 15.5 | 19 | 21.7 | |
| PANSS-Ru Marder Negative | ≤25 years | 7 | 7 | 7 | 8.5 | 10 | 11.5 | 16.25 |
| 26–35 years | 7 | 7 | 8 | 9 | 12 | 13.5 | 15.25 | |
| 36–45 years | 7 | 7 | 7 | 9 | 11 | 13 | 14.6 | |
| 46–55 years | 7 | 7 | 7 | 10 | 12 | 14.5 | 18 | |
| ≥56 years | 7 | 7 | 7 | 8 | 12 | 14.6 | 15.9 | |
| PANSS-Ru Marder Anxiety | ≤25 years | 4 | 4 | 6 | 8.5 | 10 | 10.5 | 12.25 |
| 26–35 years | 4 | 4 | 6 | 7.5 | 9 | 10 | 12.25 | |
| 36–45 years | 4 | 4 | 6 | 7 | 9 | 10.4 | 13.4 | |
| 46–55 years | 4 | 4.5 | 5.25 | 9 | 11 | 13 | 13.75 | |
| ≥56 years | 4 | 4 | 6 | 7 | 9 | 11.8 | 12.9 | |
| PANSS-Ru Marder Disorganized | ≤25 years | 7 | 7 | 7 | 10 | 12 | 13.5 | 15.75 |
| 26–35 years | 7 | 7 | 8 | 10 | 13 | 14.5 | 16 | |
| 36–45 years | 7 | 7 | 9 | 11 | 12 | 14.4 | 16.2 | |
| 46–55 years | 7 | 7.5 | 9 | 13 | 15 | 17.5 | 19 | |
| ≥56 years | 7 | 7.2 | 9 | 12 | 14.5 | 17.6 | 20.7 | |
| PANSS-Ru Marder Hostility | ≤25 years | 4 | 4 | 4 | 6.5 | 8 | 11 | 12.25 |
| 26–35 years | 4 | 4 | 4 | 6.5 | 10 | 12 | 12 | |
| 36–45 years | 4 | 4 | 5 | 7 | 9 | 10.4 | 12 | |
| 46–55 years | 4 | 4.5 | 5 | 8.5 | 11.75 | 12.5 | 13 | |
| ≥56 years | 4 | 4 | 4 | 6.5 | 8 | 11 | 12.25 | |
CGI-S: Clinical Global Impressions-Severity; PANSS-Ru: Positive and Negative Syndrome Scale-Russian version