TABLE 1.

Results of moderator analyses for chronic central animal studies

	Estimate	SE	P	Confidence interval		Residual heterogeneity
				Lower bound	Upper bound	QE	P
Gender	−0.16	0.580	.787	−1.293	0.980	42.80	<.001
Dose	−0.004	0.025	.881	−0.054	0.046	42.61	<.001
Body mass	−0.001	0.001	.437	−0.002	0.001	40.52	.002
Duration of administration	−0.01	0.022	.494	−0.057	0.028	41.56	.001

^*P < .05;

^***P < .001.