FIGURE 2.

Cortical plasticity induced by bilateral hand transplantation in an amputee. A, Hand activation in M1 before surgery and 6 mo after grafting. After receiving the graft, hand representation expanded medially to reoccupy the entire hand region. B, Center of gravity shifts over time. The right-hand representation shifted 10 mm, and the left-hand representation shifted 6 mm from the lateral to the central part of the M1 hand region. Reprinted by permission from SpringerNature: Nature Neuroscience. Cortical reorganization in motor cortex after graft of both hands. Giraux P et al.⁷⁴ Copyright 2001.