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. 2018 Apr 11;110(12):1386–1392. doi: 10.1093/jnci/djy060

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Figure 1. — Overall survival in (A) head and neck squamous cell carcinoma (HNSC; median follow-up = 536 days), (B) human papillomavirus–negative HNSC (499 days), and (C) lung squamous cell carcinoma (686 days), by genetic smoking signature status. Smoking signature was defined as highest or lowest quartile, and hazard ratios determined using Cox regression. CI = confidence interval; HNSC = head and neck squamous cell carcinoma; HPV = human papillomavirus; HR = hazard ratio; LUSC = lung squamous cell carcinoma.