A, copeptin expression in lesioned mice at baseline. Mice with reduced number of PVN glutamate neurons show no difference in serum copeptin levels. B, gene expression in the RVLM of control and lesioned animals. Grin1, gene involved in NMDA receptor expression; GluR1, gene involved in AMPA receptor expression; GAD67, Glutamic Acid Decarboxylase gene expressed in GABA neurons; GABAaR, gene involved in GABAa receptor expression. n = 4/group run in duplicate (Student's t test).