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. 2018 Sep 20;596(24):6235–6248. doi: 10.1113/JP276229

Figure 6. Urine noradrenaline (NE) levels.

Figure 6

A, urine was collected from vGlut2‐Cre mice that had previously received bilateral AAV‐flex‐taCasp3‐TEVp to the PVN (lesioned mice) and wildtype controls before and 21 days after DOCA‐salt treatment. DOCA treatment significantly increased NE levels in control mice. Lesioned mice had higher NE at baseline and lower values after DOCA treatment. There was no difference between control mice at baseline and Lesion + DOCA mice. B, spontaneous baroreceptor reflex sensitivity (SBRS) was measured in control or lesioned animals at baseline and after DOCA‐salt treatment. A, n = 16 control, n = 8 lesion; B, n = 19 control, n = 7 lesion; * P < 0.05, ** P < 0.01, *** P < 0.001 (Kruskal–Wallis test and Dunn's multiple comparison test).