Table 1.
Characteristics of Patients with Recurrent or Metastatic SCCHN, Enrolled in the NCT02643550 Phase II Clinical Trial
| Patient Characteristics, N = 31 |
N (%) |
|
|---|---|---|
| Age, median [range] | 64 [34–76] | |
| Sex | female | 10 (32) |
| male | 21 (68) | |
| ECOG | 0 | 12 (39) |
| 1 | 19 (61) | |
| HPV status | positive | 4 (13) |
| negative | 15 (48) | |
| to be determined | 12 (39) | |
| Tobacco | never | 6 (19) |
| former | 20 (65) | |
| current | 5 (16) | |
| Tumor site | oral cavity | 14 (45) |
| oropharynx | 10 (32) | |
| larynx | 4 (13) | |
| hypopharynx | 2 (6) | |
| nasopharynx | 1 (3) | |
| Type of recurrence | local | 18 (58) |
| distant | 13 (42) | |
| Prior lines of systemic therapy (overall) | Number of Previous Lines | |
| 1 | 16 (52) | |
| 2 | 10 (32) | |
| 3 | 5 (16) | |
| prior platinum | 31 (100) | |
| prior IO | 14 (45) | |
| prior cetuximab | 3 (10) | |