Table 1.
Characteristics of Patients with Recurrent or Metastatic SCCHN, Enrolled in the NCT02643550 Phase II Clinical Trial
Patient Characteristics, N = 31 |
N (%) |
|
---|---|---|
Age, median [range] | 64 [34–76] | |
Sex | female | 10 (32) |
male | 21 (68) | |
ECOG | 0 | 12 (39) |
1 | 19 (61) | |
HPV status | positive | 4 (13) |
negative | 15 (48) | |
to be determined | 12 (39) | |
Tobacco | never | 6 (19) |
former | 20 (65) | |
current | 5 (16) | |
Tumor site | oral cavity | 14 (45) |
oropharynx | 10 (32) | |
larynx | 4 (13) | |
hypopharynx | 2 (6) | |
nasopharynx | 1 (3) | |
Type of recurrence | local | 18 (58) |
distant | 13 (42) | |
Prior lines of systemic therapy (overall) | Number of Previous Lines | |
1 | 16 (52) | |
2 | 10 (32) | |
3 | 5 (16) | |
prior platinum | 31 (100) | |
prior IO | 14 (45) | |
prior cetuximab | 3 (10) |