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. 2018 Dec 7;9:627. doi: 10.3389/fgene.2018.00627

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Copyright © 2018 Aguiar, Torrecilha, Milanesi, Utsunomiya, Trigo, Tijjani, Musa, Lopes, Ajmone-Marsan, Carvalheiro, Neves, do Carmo, Hanotte, Sonstegard, Garcia and Utsunomiya.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Discovery of a B. indicus specific CNV on HMGA2 affecting navel length at yearling. (A) Relative fold increase in sequence coverage of a segment of HMGA2 intron 3 correlates with TCCTCCAAC haplotype counts in Nellore cattle. Each smoothed curve corresponds to sequence coverage averaged across samples with same haplotype count. (B) Inspection of the CNVR in additional European B. taurus and African B. indicus (marked with ^∗) breeds reveals specificity of copy gains in B. indicus. The AC090673.2 gene annotation was manually curated and predicted from expressed sequence tags (ESTs) derived from human tissues.