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. 2018 Dec 13;8:17805. doi: 10.1038/s41598-018-36205-6

Table 2.

Analysis of synergism of Cyt1Aa or mutant toxins with Cry11Aa toxin in 4th instar Aedes aegypti larvae.

Toxin S(toxin)OBSa = (Rep1 + Rep2 + Rep3)/n S(Cyt1Aa, Cry11Aa)EXPb = S(Cyt1Aa)OBS × S(Cry11Aa)OBS Expected mortalityc = (1 − S(Cyt1Aa, Cry11Aa)EXP) × 100% Observed mortalityd Cyt1Aa+Cry11Aa
Cyt1Aa 1.00 0.80 20% 90 ± 10%
A59C 1.00 0.80 20% 57 ± 20%
A61C 0.93 0.75 25.3% 83 ± 15%
Cry11Aa 0.80

aObserved survival of individual toxin S(toxin)OBS corresponds to the observed proportion of larvae that survived to the exposure to Cyt1Aa or mutant toxins. Observed mortality was 20% with Cry11Aa at 200 ng per ml and 0% with Cyt1Aa at 75 ng Cyt1Aa per ml. n = 30 larvae for each toxin tested.