Table 3.

Multivariable model of the relationship between CD4 cell count at ART initiation and combine attrition (loss to follow‐up and death) among adults in Ethiopia, Kenya, Mozambique and Tanzania 2005 to 2015 (N = 305,443)

	Univariable			Multivariable
	HR	95% CI	p‐value	aHR	95% CI	p‐value
CD4 group at ART
<50	1.50	1.48 to 1.52	<0.0001	1.56	1.53 to 1.58	<0.0001
50 to 99	1.22	1.20 to 1.24	<0.0001	1.29	1.27 to 1.32	<0.0001
100 to 199	1.03	1.01 to 1.04	0.0002	1.09	1.07 to 1.11	<0.0001
≥200	1	ref		1	ref
Age at enrolment
15 to 19	1.57	1.52 to 1.63	<0.0001	1.62	1.56 to 1.69	<0.0001
20 to 29	1.22	1.19 to 1.24	<0.0001	1.29	1.27 to 1.32	<0.0001
30 to 39	1.05	1.03 to 1.07	<0.0001	1.08	1.06 to 1.10	<0.0001
40 to 49	0.97	0.95 to 0.99	0.0081	0.97	0.95 to 0.99	0.0055
50+	1	ref		1	ref
Gender
Female	1	ref		1	ref
Male	1.23	1.19 to 1.27	<0.0001	1.28	1.26 to 1.29	<0.0001
Country
Tanzania	1	ref		1	ref
Mozambique	1.35	1.32 to 1.37	<0.0001	1.33	1.31 to 1.36	<0.0001
Kenya	0.99	0.98 to 1.01	0.55	1.00	0.98 to 1.01	0.58
Ethiopia	0.84	0.82 to 0.86	<0.0001	0.81	0.79 to 0.83	<0.0001
Year of enrolment
2005 to 2006	1	ref		1	ref
2007 to 2008	1.10	1.08 to 1.12	<0.0001	1.11	1.09 to 1.13	<0.0001
2009 to 2010	1.12	1.10 to 1.14	<0.0001	1.16	1.14 to 1.18	<0.0001
2011 to 2012	1.31	1.29 to 1.34	<0.0001	1.32	1.30 to 1.35	<0.0001
2013 to 2014	1.41	1.37 to 1.45	<0.0001	1.38	1.35 to 1.42	<0.0001

AHR, adjusted hazard ratio; ART, antiretroviral therapy.